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Isi is a name with multiple independent origins. In West African traditions, particularly among the Edo people of Nigeria, it derives from a term meaning god or divine, often used as a short form of longer theophoric names. It also functions as a Hebrew short form of names rooted in the element yishay, related to the name Jesse, meaning gift or offering. Germanic and Italian speakers additionally use Isi as a pet form of names such as Isidore or Isabella.