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Karlene is an English feminine elaboration of Karl, itself the Germanic form of Charles, derived from the Old High German element hari or karl, meaning free man or simply man. The name follows a common pattern of feminizing masculine names through the addition of the suffix -ene or -ine, producing forms such as Karla, Karlene, and Charlene. It gained use primarily in the twentieth century in English-speaking countries alongside similar coinages. Related forms include Carleen, Karleen, and Charlene.