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Addisyn is an American respelling of Addison, an English surname transferred to given-name use, derived from the Old English patronymic meaning son of Adam. Adam itself traces to the Hebrew name Adam, traditionally connected to the word for earth or red clay. The name gained popularity as a feminine given name in the United States during the early 2000s, partly propelled by the television series Grey's Anatomy, which featured a character named Addison. Variant spellings include Addison, Adyson, and Adisyn.