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Addyson is a modern American respelling of Addison, an English surname turned given name derived from the Middle English patronymic meaning son of Adam. The name Adam itself traces to the Hebrew adam, commonly interpreted as man or earth, connecting it to the biblical first man. Addison gained popularity as a feminine given name in the late twentieth and early twenty-first centuries, partly influenced by the television series Grey's Anatomy. Related forms include Addison, Adison, and Adyson.